Lakers vs. Pistons odds, prediction, line, time: 2025 NBA picks for Tuesday, Dec. 30 from proven model

The East-leading Detroit Pistons will visit the Los Angeles Lakers in a cross-conference matchup on Tuesday’s NBA schedule. Detroit (24-8) has dropped back-to-back games, most recently a 112-99 defeat to the Los Angeles Clippers on Sunday. The Lakers (20-10) ended a three-game losing streak by defeating the Sacramento Kings, 125-101, on Sunday. Detroit is 17-15 against the spread this season, while L.A. is 17-13 versus the line. Austin Reaves (calf) remains out for the Lakers, while Rui Hachimura (calf) is also out.

Tipoff is at 10:30 p.m. ET from Crypto.com Arena in Los Angeles. Detroit swept the season series last year. The latest Pistons vs. Lakers odds have Detroit as 2.5-point favorites per SportsLine consensus. The over/under for total points scored is 232.5. Before making any Lakers vs. Pistons picks, check out the NBA predictions and betting advice from the SportsLine Projection Model.